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Symbol
Name
ID
Kras
Kirsten rat sarcoma viral oncogene homolog
MGI:96680
Phenotype annotations related to renal/urinary system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Hyperphosphaturia
Increased level of L-fucose in urine
Bladder exstrophy
Epispadias
Hypospadias
Abnormality of the bladder
Horseshoe kidney
Dilatation of the renal pelvis
Hydronephrosis
Nephropathy
Nephrotic syndrome
Acute kidney injury
Renal neoplasm
Renal cell carcinoma
Abnormality of the ureter
Disease(s) Associated with KRAS
cardiofaciocutaneous syndrome
colorectal cancer
linear nevus sebaceous syndrome
Lynch syndrome
multiple myeloma
Noonan syndrome
oculoectodermal syndrome
stomach cancer

Mouse Phenotypes
renal/urinary system phenotype
abnormal kidney morphology
Availability Mouse Genotype
Krastm4.1Bbd/Krastm4.1Bbd
Krastm4Tyj/Kras+
Tg(Upk2-cre)6Xrw/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory